牛呼吸道疾病综合征防治研究进展Research advances on prophylaxis and treatment for bovine respiratory disease complex
陈平,王斐,何振富,郝怀志
摘要(Abstract):
牛呼吸道疾病综合征(BRDC)是由多种因素及病原体感染引起的系统性呼吸道疾病,在肉牛断奶、运输、混群等饲养过程中常见,是一种危害养牛业健康发展的重要疾病。该病发病情况复杂、治疗方案多样,在日常肉牛繁育生产过程中造成一定经济损失。现从牛呼吸系统疾病的病原学鉴定及分析、临床症状、诊断与检测方法、环境因素改变后的预防措施、中西医结合治疗方案等方面进行阐述,为牛呼吸道疾病的综合防治提供理论依据和技术指导。
关键词(KeyWords): 牛呼吸道疾病综合征;病原微生物;症状与诊断;预防与治疗
基金项目(Foundation): 甘肃省农业科学院农业科技创新专项计划资助项目(2020GAAS35);; 2020年甘肃省青年科技人才托举工程资助项目
作者(Author): 陈平,王斐,何振富,郝怀志
DOI: 10.16303/j.cnki.1005-4545.2021.10.29
参考文献(References):
- [1] 王洪梅,赵贵民,侯佩莉,等.牛呼吸道疾病综合征流行现状及防控技术研究进展[J].中国畜牧杂志,2015,51(16):33-39.
- [2] FULTON R W,D OFFAY J M,LANDIS C,et al.Detection and characterization of viruses as field and vaccine strains in feedlot cattle with bovine respiratory disease[J].Vaccine,2016(9):3478-3492.
- [3] ZEINELDIN M,LOWE J,DE GODOY M,et al.Disparity in the nasopharyngeal microbiota between healthy cattle on feed,at entry processing and with respiratory disease[J].Vet Microbiol,2017,208:30-37.
- [4] ABUTARBUSH S.Veterinary medicine-a textbook of the diseases of cattle,horses,sheep,pigs and goats,10th edition[J].Can Vet J,2010,51(5):541.
- [5] PRYSLIAK T,MERWE J,LAWMAN Z,et al.Respiratory disease caused by Mycoplasma bovis is enhanced by exposure to bovine herpes virus 1 (BHV-1) but not to bovine viral diarrhea virus (BVDV) type 2[J].Can Vet J,2011,52(11):1195-1202.
- [6] MCGILL J L,RUSK R A,GUERRA-MAUPOME M,et al.Bovine gamma delta T cells contribute to exacerbated IL-17 production in response to co-infection with bovine RSV and Mannheimia haemolytica[J].PLoS One,2016,11(3):e0151083.
- [7] GERSHWIN L J,VAN EENENNAAM A L,ANDERSON M L,et al.Single pathogen challenge with agents of the bovine respiratory disease complex[J].PloS one,2015,10(11):e0142479.
- [8] EL-DEEB W,ELSOHABY I,FAYEZ M,et al.Use of procalcitonin,neopterin,haptoglobin,serum amyloid A and proinflammatory cytokines in diagnosis and prognosis of bovine respiratory disease in feedlot calves under field conditions[J].Acta Trop,2020,204:105336.
- [9] JOSHI V,GUPTA V K,BHANUPRAKASH A G,et al.Haptoglobin and serum amyloid A as putative biomarker candidates of naturally occurring bovine respiratory disease in dairy calves[J].Microb Patho,2018,116:33-37.
- [10] 王嵩.牛呼吸系统疾病综合征PCR方法建立及初步应用[D].黑龙江大庆:黑龙江八一农垦大学,2014.
- [11] 郭利,王炜,张淑琴,等.牛呼吸道疾病综合征相关病毒BVDV、BPIV3、IBRV和BRSV多重PCR检测方法的建立[J].特产研究,2014,36(1):12-16.
- [12] 谢志勤,谢芝勋,范晴,等.牛传染性鼻气管炎病毒和牛病毒性腹泻病毒双重荧光定量PCR检测方法的建立[J].动物医学进展,2019,40(3):20-25.
- [13] 冯旭飞,刀筱芳,李定菲,等.溶血性曼氏杆菌和多杀性巴氏杆菌双重PCR检测方法的建立及应用[J].中国兽医科学,2014,44(6):624-629.
- [14] 何琪富,郭紫晶,李然,等.牛冠状病毒RT-PCR检测方法的建立及应用[J].畜牧兽医学报,2018,49(10):2292-2298.
- [15] 沈付娆,杨建乐,赵贵民,等.牛冠状病毒SYBR Green Ⅰ实时荧光定量PCR检测方法的建立及初步应用[J].中国兽医杂志,2016,52(6):22-24.
- [16] MITRA N,CERNICCHIARO N,TORRES S,et al.Metagenomic characterization of the virome associated with bovine respiratory disease in feedlot cattle identified novel viruses and suggests an etiologic role for influenza D virus[J].J Gen Virol,2016,97(8):1771-1784.
- [17] JOHNSTON D,EARLEY B,CORMICAN P,et al.Illumina MiSeq 16S amplicon sequence analysis of bovine respiratory disease associated bacteria in lung and mediastinal lymph node tissue[J].BMC Vet Res,2017,13(1):118.
- [18] PUCHALSKI A,URBAN-CHMIEL R,DEC M,et al.The use of MALDI-TOF mass spectrometry for rapid identification of Mannheimia haemolytica[J].J Vet Med Sci,2016,78(8):1339-1342.
- [19] CORNELISSEN J B,DE BREE F M,VAN DER WAL F J,et al.Mycoplasma detection by triplex real-time PCR in bronchoalveolar lavage fluid from bovine respiratory disease complex cases[J].BMC Vet Res,2017,13(1):97.
- [20] MURRAY G M,O'NEILL R G,LEE A M,et al.The bovine paranasal sinuses:bacterial flora,epithelial expression of nitric oxide and potential role in the in-herd persistence of respiratory disease pathogens[J].PLoS One,2017,12(3):e0173845.
- [21] COCKRUM R R,SPEIDEL S E,SALAK-JOHNSON J L,et al.Genetic parameters estimated at receiving for circulating cortisol,immunoglobulin G,interleukin 8,and incidence of bovine respiratory disease in feedlot beef steers[J].J Anim Sci,2016,94(7):2770-2778.
- [22] ZEINELDIN M M,EL-RAOF Y,EL-ATTAR H A,et al.Lung ultrasonography and computer-aided scoring system as a diagnostic aid for bovine respiratory disease in feedlot cattle[J].Glob Vet,2016,17(6):588.
- [23] BASOGLU A,BASPINAR N,TENORI L,et al.Plasma metabolomics in calves with acute bronchopneumonia[J].Metabolomics,2016,12(8):128.
- [24] JOHNSTON D,KENNY D A,MCGEE M,et al.Electronic feeding behavioural data as indicators of health status in dairy calves[J].Ir J Agric Food Res,2016,55(2):159-168.
- [25] 季文恒,吴娅琴,翟肖辉,等.牛支原体疫苗的研究进展[J].中国畜牧兽医,2018,45(3):763-769.
- [26] BüRKI S,FREY J,PILO P.Virulence,persistence and dissemination of Mycoplasma bovis[J].Vet Microbiol,2015,179(1/2):15-22.
- [27] NICHOLAS R A,AYLING R D,MCAULIFFE L.Vaccines for mycoplasma diseases in animals and man[J].J Comp Pathol,2009,140(2/3):85-96.
- [28] PHILIPPE-REVERSAT C,HOMER D,HAMERS C,et al.Duration of immunity of a four-valent vaccine against bovine respiratory diseases[J].Acta Vet Brno,2017,86(4):325-332.
- [29] PUSCHNER B.Veterinary clinics of north America:food animal practice[J].Vet Clin Food Anim,2020,36(2):239-508.
- [30] CHEN J,YANG C,TIZIOTO P C,et al.Expression of the bovine NK-lysin gene family and activity against respiratory pathogens[J].PLoS One,2016,11(7):e0158882.
- [31] SGOIFO R,VANDONI S L,BONFANTI M,et al.Effects of arrival medication with gamithromycin on bovine respiratory disease in feedlot cattle in Italy[J].Int J Appl Res Vet Med,2010,8(2):87-96.
- [32] THIRY J,GONZáLEZ-MARTíN J V,ELVIRA L,et al.Treatment of naturally occurring bovine respiratory disease in juvenile calves with a single administration of a florfenicol plus flunixin meglumine formulation[J].Vet Rec,2014,174(17):430.
- [33] 韩潇潇,陈颖钰,郭爱珍.牛支原体病综合防制措施[J].养殖与饲料,2012(11):29-32.
- [34] AMAT S,BAINES D,ALEXANDER T W.A vapor-phase assay for evaluating the antimicrobial activities of essential oils against bovine respiratory bacterial pathogens[J].Lett Appl Microbiol,2017,65(6):489-495.
- [35] 沈宏鹏.犊牛呼吸道疾病诊断与治疗措施[J].畜牧兽医科学,2020(1):108-109.
- [36] 冯海鹏,辛蕊华,张凯,等.中兽药复方组合与抗生素防治肉鸡呼吸道疾病的协同效应[J].中国畜牧兽医,2020,47(3):940-947.
- [37] 付祥栋.奶山羊常见呼吸道疾病的中西医治疗[J].中国乳业,2020(5):57-58.
- [38] 廖勇.中医药防治猪呼吸道疾病的方法[J].中国畜禽种业,2020,16(7):167.